Windows Subsystem Layer 2 does not work with VMWare or Virtual Box

What is Windows Subsystem Layer 2 ?

Will I be able to run WSL 2 and other 3rd party virtualization tools such as VMware, or Virtual Box? NO

Some 3rd party applications cannot work when Hyper-V is in use, which means they will not be able to run when WSL 2 is enabled. Unfortunately, this does include VMware, and versions of Virtual Box before Virtual Box 6 (Virtual Box 6.0.0 released in December 2018 now supports Hyper-V as a fallback execution core on a Windows host!)

We are investigating ways to help resolve this issue. For example, we expose a set of APIs called Hypervisor Platform that third-party virtualization providers can use to make their software compatible with Hyper-V’s. This lets applications use the Hyper-V architecture for their emulation such as the Google Android Emulator, and Virtual Box 6 and above which are both now compatible with Hyper-V.

https://devblogs.microsoft.com/commandline/wsl-2-post-build-faq/

WSL 2 Linux Kernel will be updated by Windows Update

That's right the Linux 4.19 will be fully CVE updated and managed by Windows Update.